Abstract Background Ligand-binding proteins play key roles in many biological processes.Identification of protein-ligand binding residues is important in understanding the biological functions of proteins.Existing computational methods can be roughly categorized as sequence-based or 3D-structure-based methods.All these methods are based on traditio

Multiple scoring systems (including rank and score functions; MSS) have been widely used in multiple regression, intelligent biometric systems, multiple artificial neural nets, combining pattern classifiers, ensemble methods, machine learning and artificial intelligence (AI), data and information fusion, preference ranking, and deep learning.Combin

INTRODUCTION: Recent studies have shown that histones, the chief protein component of chromatin, are released into the extracellular space during sepsis, trauma, and ischemia-reperfusion injury, and act as major mediators of the death of an organism.This study was designed to elucidate the cellular and molecular basis of histone-induced lethality a

The anti-counterfeiting is an ongoing problem whose solution requires significant human and financial resources.Eventual additional expenses are reflected in the final price of a protected product that means the customers pay for anti-counterfeiting.Simple and inexpensive method for document authenticity verification development and implementation,